Can Glutathione Make Your Skin Whiter?

Before I answer that question, let me state this idea first before I give my answer to that query. Before a certain drug can exert its effect on the intended region of the body it must be well absorbed. Well absorbed means that a certain minimum level of the drug concentration must pass to the blood stream and go to the site of action. Sometimes, the effect of a certain chemical must work with some molecules found in the body to create the desired effect or vice versa.

In the case of oral absorption (pills, capsules, tablets etc.,), I am sorry but at the moment it can’t reach the desired concentration to the blood stream. However, IV administration is possible.

According to http://en.wikipedia.org/wiki/Glutathione under the header of supplementation “Raising GSH levels through direct supplementation of glutathione is difficult. Research suggests that glutathione taken orally is not well absorbed across the gastrointestinal tract. In a study of acute oral administration of a very large dose (3 grams) of oral glutathione, Witschi and coworkers found "it is not possible to increase circulating glutathione to a clinically beneficial extent by the oral administration of a single dose of 3 g of glutathione."^[23][24] -- This means that oral administration is not possible at the moment, unless they found a new way of protecting the Glutathione from the GIT tract.

In the case of Glutathione as an effective whitening agent. Yes, the study appears to have an effect.

According to http://en.wikipedia.org/wiki/Glutathione “Glutathione has recently been used as an inhibitor of melanin in the cosmetics industry. In countries like Japan and the Philippines, this product is sold as a whitening soap. Glutathione competitively inhibits melanin synthesis in the reaction of tyrosinase and L-DOPA by interrupting L-DOPA's ability to bind to tyrosinase during melanin synthesis. The inhibition of melanin synthesis was reversed by increasing the concentration of L-DOPA, but not by increasing tyrosinase. Although the synthesized melanin was aggregated within 1 h, the aggregation was inhibited by the addition of glutathione. These results indicate that glutathione inhibits the synthesis and agglutination of melanin by interrupting the function of L-DOPA." The entire study will be seen in this address http://www.jstage.jst.go.jp/article/yakushi/128/8/1203/_pdf/-char/ja/

Can a whitening agent be delivered using soaps? The answer is probably no. Unless they have an evidence that the right concentration of the medicine is being absorbed on the skin.

Soaps are cleansers; it will remove both oil and dirt on the skin including any other material in contact with it. Sorry, this is not the best medium to deliver this medicine at the moment. 

                         Chemical Formula of Glutathione

Can Glutathione Reduce Weight?

Hi there, got a question from a friend...
here is the first one...
Can Glutathione reduce weight?

Based on http://en.wikipedia.org/wiki/Glutathione. There is no evidence that it can reduce weight. (Sorry guys!, unless you have a new study material which says so).

However, taking it as supplement can do some benefit.
1. Basically it is a good antioxidant. This means that it can protect the cell from harmful free radicals which lead to a lot of things. Such as premature aging, diseases, etc.,

                                            Chemical Formula of Glutathione

Standing Up After Eating and Bigger Belly

Hmmnnn.... This is a tricky question because I do practice this step of standing after eating. I am not sure about the exact answer to this and I am following 2 blogs regarding this concern.

Here are the blogs first before I give my personal opinion on this topic.

1. http://www.steadyhealth.com/stomach_expands_after_eating_t87678.html

2. http://www.flat-stomach-exercises.com/stomach-bloating.html

OK, here is my opinion on the matter.

The stomach is made up of an abdominal muscle. Like any other muscle, we need to work this out to make it strong and firm. The more you work this out, the firmer it gets. But caution, if you are already flabby on this area (Just hold your belly and your sides with your thumb and pointing finger and pinch it. If you are able to pinch it easily it means you are confirmed flabby. Yes, sorry to say, I have this too).

OK so what do we do with it?

1. Guy's there is no short cut to this, do cardio(... unless you got so much money to spend on the operating room which will provide you a temporary solution unless you maintain it by diet and exercise.) How? It is best to do it with friends. Enjoyable workout will make cardio fun. Fun is the best way of keeping everyone motivated in doing this task. Cardio can come from swimming, running, fast walking, dancing or anything that will give you fast movements.

2. Diet. Eating the right food. Less carbo and fats during the night time. Eat like a king in the morning (properly of course with less fat, high protein, high fiber and moderate carbo), Moderate eating in the afternoon and eat like a beggar at night (less of everything, my friend avoid carbo at night, I suggest to eat less like ½ a cup if you can. If you are sick, please consult a dietitian and doctor about this).

3. We need to differentiate also bloating (Gas production of the stomach) from a flabby stomach. If you are bloated after eating, there are OTC(over the counter) medicines which can help you temporarily (it is better if you seek medical advice when you feel that something is wrong with your stomach after eating) but you are flabby? (With beer belly and all), please read number 2.

4. When your on the street, try observing the people living and working there. Unless of course if they are malnourished (When they have bloated stomach). They have toned muscle and flat stomach (most of them right?). They only eat the food that they need and nothing in excess. If you want to loose those flab’s, you may want to share those excesses with them hehehe.

5. You can also take natural supplements which can curve your appetite like Garcinia cambogia.

**There are a lot of things to talk about this topic so I will break it down on another session. :) *